Vitamin B3 (Niacin) is a white crystalline vitamin, also called nicotinic acid and a structural form of vitamin B3, a vital component of dietary vitamins. Niacin comes from the diet in several forms, including as a supplement in some foods and as a drug in another form. It is also found in some pharmaceutical drugs and in some dental preparations. Therefore check out this page for more info.

Clinical trials have shown that niacin reduces cholesterol levels and may lower blood pressure. It has a pronounced antioxidant effect and may inhibit the formation of low-density lipoprotein or plaque, which can harden and lead to coronary artery disease. However, there are conflicting views on the relation between low levels of niacin and stroke, and on the safety of using this vitamin in patients with high blood pressure or diabetes.


The beneficial effects of niacin were studied in two large meta-analyses published in the Journal of American Medical Association and the New England Journal of Medicine. Both studies showed a significant reduction in cardiovascular risk factors for people who had increased the recommended daily allowance by 30%. In both studies, the pooled estimate was not significantly different, meaning that there was no significant difference in risk between the groups. Niacin lowers LDL cholesterol (LDL) by increasing triglycerides in the bloodstream, blood pressure in patients with hypertension and increasing the action of selective serotonin reuptake inhibitors, a type of antidepressant. It does this by preventing cholesterol from being absorbed in the blood by stopping cholesterol trans-actions at the level of the blood cells. In addition to these effects, niacin increases the good cholesterol HDL (HDL), improves the control of diabetes and minimizes blood clots in arterial walls.


There are many reasons to believe that niacin may improve cardiovascular health. For instance, it appears that the increase in HDL is related to an increase in niacin and decreases the proportion of LDL cholesterol in circulation. However, there is conflicting view on whether dietary supplementation of niacin improves the control of diabetes, triglycerides, or blood pressure. Some researchers have stated that while niacin improves lipid profile, the evidence is unclear as to whether it causes a decreased risk of stroke, heart disease or other heart problems. You can get in touch with an ideal Niacin Supplements shop through this link.


Preliminary research suggests that there may be a protective effect of niacin on heart disease. The researchers studied 912 patients with mild heart disease, including four with atherosclerosis and seven with congestive cardiomyopathy. The researchers measured blood serum levels of nicotinic acid (which is related to vitamin B3), high-density lipoprotein cholesterol, total cholesterol, high-density triglyceride and ratio of high-to-low density lipoproteins. They found that people with elevated total cholesterol, triglycerides and ratios of triglycerides and high-density lipoproteins had a significantly lower risk of congestive cardiomyopathy, type 2 diabetes, and heart disease. They also showed that people with higher levels of HDL (good) cholesterol had a lower risk of heart disease or coronary artery disease.
The results of the study were consistent with the hypothesis that niacin reverses lipoprotein abnormalities associated with type 2 diabetes, heart disease and other heart conditions. However, the authors warn against interpreting the results of this study as conclusive evidence in support of the benefits of niacin. They caution that since the LDL/HDL cholesterol ratio was not controlled, it is impossible to determine if the treatment lowered the levels of LDL or increased the levels of HDL. It is also impossible to determine whether the HDL levels were influenced by the treatment. The researchers emphasize that more research is needed to strengthen the hypothesis of the benefits of niacin in LDL/HDL cholesterol ratios in patients with mild cholecystitis. Knowledge is power and so you would like to top up what you have learned in this article at https://en.wikipedia.org/wiki/DNA_repair.

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